Week 3 NFL picks, odds, 2023 best bets from advanced model: This five-way football parlay pays 25-1

The Los Angeles Chargers have lost a pair of games by a combined five points to open the season, putting them in a must-win situation heading into their game at Minnesota during the Week 3 NFL schedule. Los Angeles lost to Tennessee in overtime in Week 2 despite entering the game as a 2.5-point favorite. The Chargers are 1-point road favorites at Minnesota in the Week 3 NFL odds, one of the slimmest NFL Vegas lines of the week.

Meanwhile, New England is hitting the road for the first time this season after suffering back-to-back home losses, destroying plenty of NFL bets along the way. The Patriots are 2.5-point road favorites against the Jets, who are coming off a 30-10 loss at Dallas. Before you make any Week 3 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2023 NFL season on an incredible 164-117 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 18-9 roll on top-rated NFL picks since Week 7 of last season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has locked in five confident NFL best bets for Week 3. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 3 NFL picks at SportsLine.

Top Week 3 NFL picks

After simulating every game 10,000 times, the model is high on the Baltimore Ravens (-8) to cover at home against the Indianapolis Colts. Indianapolis snapped an eight-game losing streak with a 31-20 win at Houston last week, but it will be difficult for the Colts to build on that victory this week. They have lost five of their last six games against Baltimore and only covered the spread once in their last five games overall.

Baltimore has been trending in the opposite direction since the end of last season, covering the spread in five of its last six games. The Ravens cruised to a 25-9 win over Houston in their opener before notching an impressive road win at Cincinnati last week. Quarterback Lamar Jackson has already racked up nearly 500 total yards and three touchdowns, connecting with wide receiver Zay Flowers 13 times for 140 yards on 15 targets.

Indianapolis is playing without running back Jonathan Taylor (ankle), and quarterback Anthony Richardson is questionable due to a concussion. Those injuries will make it even more difficult for the Colts to compete with the Ravens, who are covering the spread in almost 60% of the latest simulations. See which other NFL parlay picks to make here.

How to make Week 3 NFL parlays

The model also jumped on four other NFL matchups where it says the line is way off, including three favorites who cover with points to spare. You can only see the model’s NFL Week 3 best bets and parlay at SportsLine. 

What are the model’s top Week 3 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 3 NFL best bets from a model on a 164-117 run on top-rated picks, and find out.