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Broncos vs. Browns odds, line, spread: Thursday Night Football picks, predictions from NFL model on 125-85 run

Written by on October 21, 2021

The Cleveland Browns (3-3) will host Teddy Bridgewater and the Denver Broncos (3-3) on Thursday Night Football in Week 7. The Browns have been decimated by injuries early in the season, with Nick Chubb (calf), Kareem Hunt (calf), Baker Mayfield (shoulder) and potentially several others slated to miss Thursday Night Football. The Broncos started 3-0 for the first time since 2016 before dropping their next three games. Both teams are 3-3 against the spread in 2021.

Kickoff from FirstEnergy Stadium is set for 8:20 p.m. ET. Cleveland is favored by two points in the latest Broncos vs. Browns odds from Caesars Sportsbook, while the Over-Under is 41. Before locking in any Browns vs. Broncos picks, you need to check out the NFL predictions and analysis from the proven SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up almost $7,700 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 7 of the 2021 season on an incredible 125-85 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated Browns vs. Broncos 10,000 times and just revealed its coveted NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Now, here are several NFL odds and betting lines for Browns vs. Broncos:

  • Broncos vs. Browns spread: Browns -2
  • Broncos vs. Browns over-under: 41 points 
  • Broncos vs. Browns money line: Cleveland -125, Denver +105
  • CLE: Browns are 7-3 ATS in their last 10 Thursday games  
  • DEN: Over is 4-1 in Broncos’ last five games following a straight-up loss  

Featured Game | Cleveland Browns vs. Denver Broncos

Why the Browns can cover

The Browns have been hit hard by the injury bug in 2021. Odell Beckham Jr., Nick Chubb, Jack Conklin, A.J. Green, Kareem Hunt, Baker Mayfield, Jeremiah Owusu-Koramoah, Malcolm Smith, JC Tretter, and Jedrick Wills all missed practice Monday, and several other key players were listed on the team’s injury report.

With Mayfield unable to go, the Browns will turn to veteran backup Case Keenum, who was Denver’s starting quarterback in 2018. D’Ernest Johnson is expected to get the start at running back for Cleveland.

Defensively, the Browns are in better shape, but still have several players battling nagging injuries. With Denver’s offensive line struggling, Garrett and fellow defensive end Jadeveon Clowney could have a field day. 

Why the Broncos can cover

Denver has a two-headed combo leading their rushing attack. Melvin Gordon leads the Broncos with 70 carries for 332 yards with two touchdowns. Rookie Javonte Williams is right behind him with 65 carries for 300 yards and one touchdown. Both tailbacks have been effective catching passes out the backfield as well.

Gordon has snagged 13 passes for 119 yards, while Williams has caught 15 for 90. This tandem will have their work cut out for them against one of the best run defenses in the league, as Cleveland allows only 87 rushing yards per game. Rookie linebacker Jeremiah Owusu-Koramoah is the Browns’ leading tackler, but he is doubtful for this game due to an ankle injury. 

How to make Broncos vs. Browns picks 

SportsLine’s model is leaning over on the point total, projecting the teams to combine for 44 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see the model’s Broncos vs. Browns picks at SportsLine.

So who wins Browns vs. Broncos on Thursday Night Football? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Browns vs. Broncos spread to jump on, all from the advanced model that is up almost $7,700 on its NFL picks, and find out.

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