Stanford vs. Arizona State odds, line: 2021 college football picks, Week 6 predictions from model on 12-4 run

Stanford and No. 22 Arizona State will square off in a Pac-12 showdown on Friday night. The Stanford Cardinal (3-2) are coming off the biggest of their season, beating No. 8 Oregon 31-24 in overtime. The Sun Devils (4-1) defended their home turf and beat UCLA 42-23 in Week 5. Arizona State has won two games in a row and has its eyes set on its third. 

Kickoff from Sun Devil Stadium is set for 10:30 p.m. ET. The Sun Devils are favored by 13 points in the latest Stanford vs. Arizona State odds from Caesars Sportsbook, while the over-under for total points is set at 51.5. Before making any Arizona State vs. Stanford picks, be sure to see the college football predictions and betting advice from SportsLine’s proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It also enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Stanford vs. Arizona State and revealed its CFB picks and predictions. Visit SportsLine now to see the model’s picks. Here are the college football odds and betting lines for Arizona State vs. Stanford:

• Stanford vs. Arizona State spread: Sun Devils -13
• Stanford vs. Arizona State over-under: 51.5 points
• Stanford vs. Arizona State money line: Stanford +400, Arizona State -550
• ASU: The Over is 4-0 in Arizona State’s last four conference games
• STAN: The Cardinal are 5-1-1 ATS in their last seven road games

Featured Game | Arizona State Sun Devils vs. Stanford Cardinal

Why Stanford can cover

The Cardinal won a physical conference matchup last week, defeating No. 8 Oregon 31-24 in overtime at home. Stanford jumped out to a 17-7 halftime lead before Oregon rallied back to take a 24-17 advantage. Oregon was called for a holding penalty on the last play of the game, giving Stanford one more chance. Sophomore quarterback Tanner McKee threw a jump ball to the corner of the end zone and junior receiver Elijah Higgins went up and snagged it to tie the game. 

McKee then threw a slant to sophomore receiver John Humphreys, who fought his way into the end zone to give Stanford the lead in overtime. McKee went 20-of-36 for 230 yards with three touchdowns to lead the Cardinal to an upset win. Stanford showed resilience and fight in its comeback victory against Oregon and will look to bring that same grit on the road against No. 22 Arizona State. 

Why Arizona State can cover

The Sun Devils roll into this matchup with the No. 1 ranked offense in the Pac-12. Arizona State’s well-balanced offense averages 442.8 total yards per game. The Sun Devils have a conference-high 18 rushing touchdowns while averaging 203.4 yards per game on the ground. Against UCLA, Arizona State rushed for 178 yards with three touchdowns. 

Redshirt senior Rachaad White and sophomore DeaMonte Trayanum led the rushing attack against the Bruins. White had nine carries for 69 yards with two touchdowns, including a 49-yard touchdown run. Trayanum had 16 carries for 68 yards and another score. This running back tandem can give the Stanford defense fits on Friday night.

How to make Arizona State vs. Stanford picks

SportsLine’s model is leaning over on the total, projecting 59 combined points. It also has generated an against the spread pick that hits in almost 60 percent of simulations. You can get the pick over at SportsLine.

So who wins Stanford vs. Arizona State? And which side of the spread hits nearly 60 percent of the time? Visit SportsLine now to see which side of the Arizona State vs. Stanford spread to back, all from the advanced model that is up almost $3,400 on its top-rated college football spread picks, and find out.

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