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Week 13 NFL injury roundup: Updates on Baker Mayfield, C.J. Stroud, Daniel Jones and more

Written by on November 29, 2025

Week 13 NFL injury roundup: Updates on Baker Mayfield, C.J. Stroud, Daniel Jones and more

Week 13 NFL injury roundup: Updates on Baker Mayfield, C.J. Stroud, Daniel Jones and more

There have already been four games played in Week 13, but with no teams on a bye, there are plenty more on tap for this weekend.

And while most of the players involved in these matchups will be able to participate, there are of course some who have either been ruled out or whose statuses are up in the air. To keep you updated, we’ve compiled all the final injury reports for Sunday’s slate, plus some initial notes for the “Monday Night Football” matchup between the New England Patriots and New York Giants.

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Los Angeles Rams at Carolina Panthers (+10.5)

TEAMPLAYERPOSITIONINJURYSTATUS
RamsKamren KinchensSShoulderQuestionable
David QuessenberryOLGroinQuestionable
Poona FordDLCalfQuestionable
PanthersJaycee HornCBConcussionOut
Cade MaysCAnkleOut
Chandler ZavalaOGCalfOut
Christian RozeboomLBHip/HamstrongOut
Claudin CherelusLBConcussionOut

The Rams’ secondary has been playing quite well but could be without an important piece here, while the defensive front could take a hit in the run defense department as well.

Carolina will be without its top cornerback, a significant issue against one of the best wide receiver duos in the NFL. The offensive line is also banged up, and the linebacker corps will still have a pair of absences despite the return of Trevin Wallace, who has no injury designation.

San Francisco 49ers at Cleveland Browns (+4.5)

TEAMPLAYERPOSITIONINJURYSTATUS
49ersEddy PineiroKHamstringOut
Tatum BethuneLBAnkleOut
Sam OkuayinonuDEAnkleOut
BrownsBrenden BatesTEAnkleOut
Adin HuntingtonDTQuadOut
Alex WrightDEQuadOut
Jerome FordRBHamstringQuestionable

San Francisco will have a backup kicker here and will also be down yet another linebacker with Fred Warner already out.

Things are fairly clean for the Browns, though they could miss Wright as a rotational rusher. If Ford can’t go, the backfield will be entirely split between rookies Quinshon Judkins and Dylan Sampson.

Houston Texans at Indianapolis Colts (-3.5)

TEAMPLAYERPOSITIONINJURYSTATUS
TexansAjani CarterCBHamstringOut
Jamal HillLBHamstringOut
ColtsJaylon CarliesLBAnkleOut

C.J. Stroud will make his return from a concussion for the Texans. The report is otherwise pretty clean.

Daniel Jones is good to go for the Colts despite reportedly having a fractured fibula. They report is otherwise pretty clean.

New Orleans Saints at Miami Dolphins (-5.5)

TEAMPLAYERPOSITIONINJURYSTATUS
SaintsAlvin KamaraRBKnee/AnkleOut
Chris OlaveWRBackQuestionable
DolphinsRasul DouglasCBFoot/AnkleQuestionable
Austin JacksonOTToeQuestionable
Benito JonesDTAnkleQuestionable
Darren WallerTEPectoralQuestionable

New Orleans will be without Kamara, which means rookie Devin Neal, who is off the injury report, will lead the backfield. Olave’s potential absence would obviously be a significant burden for the offense to bear. 

The Dolphins have been shorthanded in the defensive backfield all season. The offense could take a hit if Jackson is unable to play, but could get a lift if Waller is able to return from his injury.

Atlanta Falcons at New York Jets (+2.5)

TEAMPLAYERPOSITIONINJURYSTATUS
FalconsDrake LondonWRKneeOut
Josh WoodsILBHamstringOut
Malik VerdonILBShoulderOut
Chris LindstromOGFootQuestionable
JetsJarvis Brownlee Jr.CBHipQuestionable
Harrison PhillipsDLFootQuestionable

Kirk Cousins will again be without his top wide receiver and could be missing the team’s best offensive lineman as well. 

The Jets have a fairly clean report here, but Brownlee and Phillips are important defenders for a unit that recently traded Sauce Gardner and Quinnen Williams but has played surprisingly well since doing so.

Arizona Cardinals at Tampa Bay Buccaneers (-2.5)

TEAMPLAYERPOSITIONINJURYSTATUS
CardinalsTrey BensonRBKneeOut
Emari DemercadoRBAnkleOut
Will HernandezOLHip/KneeOut
Christian JonesOLKneeOut
Walter Nolen IIIDLKneeOut
Kelvin BeachumOLGroinQuestionable
Hayden ConnerOLKneeQuestionable
Marvin Harrison Jr.WRIllnessQuestionable
Zonovan KnightRBKneeQuestionable
Max MeltonCBHeelQuestionable
BuccaneersBenjamin MorrisonCBHamstringOut
Rashad WisdomSQuadOut
Ben BredesonGHamstringQuestionable
Jamel DeanCBHipQuestionable
Bucky IrvingRBShoulder/FootQuestionable
Baker MayfieldQBLeft ShoulderQuestionable
Anthony NelsonOLBRibsQuestionable
Haason ReddickOLBAnkle/KneeQuestionable

The Cardinals are very banged up in the backfield and could be down to just Michael Carter and practice squad players if Knight can’t give it a go. They also have several injuries up front on both sides of the ball. Harrison was limited all week in his attempt to return from appendicitis. Melton got back to a limited practice on Friday after not participating on Thursday.

Morrison is a big absence in the defensive backfield for Tampa. Irving is expected to return to the fold and be part of a hot-hand rotation along with Rachaad White and Sean Tucker, per coach Todd Bowles, who also said Mayfield is trending toward playing. Nelson and Reddick are important pieces of the defensive front.

Jacksonville Jaguars at Tennessee Titans (+6.5)

TEAMPLAYERPOSITIONINJURYSTATUS
JaguarsPatrick MekariOLConcussionOut
Eric MurraySNeckOut
Travon WalkerDEKneeOut
Chuma EdogaOLCalfOut
TitansJalyn Armour-DavisCBAchillesOut
Kendell BrooksSConcussionOut
Lloyd CushenberryCFootOut
Shy TuttleDLConcussionOut
Elic AyomanorWRHamstringQuestionable
Chig OkonkwoTEFootQuestionable
Xavier WoodsSHamstringQuestionable

Brian Thomas Jr. has no injury designation and is set to return after his absence. The Jags are missing a couple pieces along the offensive line, as well as one of their best pass rushers, which could help the Titans keep Cam Ward protected for a change.

Speaking of Ward, he will be without his starting center, but could get some help in the receiving corps if Ayomanor is ready to return and Okonkwo plays through his designation. Woods is questionable after missing the game last week. 

Minnesota Vikings at Seattle Seahawks (-9.5)

TEAMPLAYERPOSITIONINJURYSTATUS
VikingsDonovan JacksonOLAnkleOut
J.J. McCarthyQBConcussionOut
Christian DarrisawOLKnee/FootQuestionable
Jonathan GreenardOLBShoulderQuestionable
Theo JacksonSNeckQuestionable
Josh MetellusSKnee/ShoulderQuestionable
Jalen RedmondDLHipQuestionable
SeahawksGeorge HolaniRBHamstringOut
Rylie MillsDEKneeOut
Ty OkadaSObliqueQuestionable

McCarthy is out with a concussion, leaving Max Brosmer to make his first career start. The Vikings won’t have one of their starting guards in front of him. On defense, there are key potential absences at safety and up front — particularly Greenard and Metellus.

It’s a pretty clean report for the Seahawks.

Las Vegas Raiders at Los Angeles Chargers (-9.5)

TEAMPLAYERPOSITIONINJURYSTATUS
RaidersMichael MayerTEAnkleOut
Jordan MeredithOLAnkleQuestionable
Adam ButlerDLIllnessQuestionable
Darnay HolmesCBIllnessQuestionable
Zamir WhiteRBIllnessQuestionable
ChargersOmarion HamptonRBAnkleOut
Otito OgbonniaDLElbowQuestionable

Mayer being out means Brock Bowers will likely play close to every snap for Vegas. The Raiders are already down Jackson Powers-Johnson up front and could be without another offensive lineman. And it looks like there might be an illness going through the locker room.

Both Hampton and Ogbonnia are on injured reserve. Hampton isn’t quite ready, but Ogbonnia might be.

Buffalo Bills at Pittsburgh Steelers (+3.5)

TEAMPLAYERPOSITIONINJURYSTATUS
BillsTerrel BernardLBElbowOut
Spencer BrownOTShoulderOut
Dion DawkinsOTConcussionOut
Josh PalmerWRAnkleQuestionable
SteelersBroderick JonesOTNeckOut
Derrick HarmonDTKneeOut

Buffalo will be without one of its best defenders as well as its bookend tackles for this game. Those are massive absences. 

The Steelers won’t have their starting left tackle, as well as an important interior lineman on their defense.

Denver Broncos at Washington Commanders (+5.5)

TEAMPLAYERPOSITIONINJURYSTATUS
BroncosNate AdkinsTEKneeOut
Jonah EllissLBHamstringQuestionable
CommandersNoah BrownWRGroin/Knee/RestOut
Jayden DanielsQBElbowOut
Drake JacksonDEKneeOut
Will HarrisSAnkleQuestionable
Tyler OttLSIllness/BackQuestionable

The Broncos’ report is fairly clean, but Elliss’ absence would be a blow if he can’t play.

Washington will again be without its starting quarterback and No. 3 receiver, but Terry McLaurin is off the injury report and will play.

New York Giants at New England Patriots (-7.5) (Monday)

The Giants announced on Friday that Jaxson Dart, who missed last week’s game with a concussion, will start on Monday. Dexter Lawrence, Kayvon Thibodeaux and Demetrius Flannigan-Fowles didn’t practice for the Giants on Friday. Paulson Adebo, Wan’Dale Robinson and Darius Slaytonn were limited.

Harold Landry and Jared Wilson sat out Friday’s practice for New England, while Jahlani Tavai was limited. Will Campbell is on injured reserve.

The post Week 13 NFL injury roundup: Updates on Baker Mayfield, C.J. Stroud, Daniel Jones and more first appeared on OKC Sports Radio.


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